Preheat the oven to 350 degrees F.
Add the beef to a large cast iron skillet or Dutch oven over medium-high heat. Season with the Original or your favorite blend. Continue cooking until the meat is about half-way browned. Stir in the onions. Continue cooking until the meat has fully browned. Drain any excess grease, if needed.
Remove half of the beef mixture from the skillet and place in a bowl. Set aside.
Stir in the mushroom soup and ½ can of corn. Note, if using creamed corn, stir in about 3 tablespoons of all-purpose flour, to thicken.
Evenly spread half the sour cream mixture on top, followed by 1 cup of cheese.
Evenly top the mixture with the reserved beef. Evenly spread another layer with the remaining sour cream, corn and cheese.
Top the casserole with the biscuits and lightly press the biscuits down. Sprinkle the tops of the biscuits with pepper and garlic powder.
Bake for about 15 minutes, or until biscuits are set and golden brown. Serve warm.